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  • Chemical Biology

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    Item specifics

    Condition:
    Used: An item that has been previously used. See the seller’s listing for full details and description of ... Read moreabout the condition
    Type: Military Personnel
    Era: 1751-1815 Brand: Britains
    Scale: 1:32 MPN: Does Not Apply
    Number of Pieces: 11-20 Material: Painted Lead
    Country/Region of Manufacture: United Kingdom Nationality: French
    EAN: Does not apply

    Edu49871 1 48 Eduard color Pe - A-4e Skyhawk Detail Set (for Use With The -

    Here’s some medicinal chemistry combined with synthetic biology for you. Many people are used to thinking in terms of finding small-molecule probes for various cell targets, and those are valuable things. But what if you want to control a certain population of (for example) ion channels, but there aren’t any compounds that will do the… Carrera WIRELESS+ Receiver for Carrera Digital 124 Digital 132 -CA10112
  • Chemical News

    09847 Trumpeter Display Case Box Model 165X120X360mm Showcase Battleship Tank

    SBD 5 DAUNTLESS - ITA-02673 I was interested to see this paper, which goes into detail on a chemical phenomenon that many have seen but no one understands very well: triboluminescence. That word meets with a blank stare or instant recognition; there’s not much in between. It means “emission of light when a material is physically broken”, and that encompasses… Trumpeter 01014 1 35 Russia BM21 Grad Late Version
  • Analytical Chemistry

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    I suppose I deserve this one. Some years ago on the blog, I wrote about my days in grad school having to learn about symmetries and vibrational spectroscopy. Sparingly has that knowledge come in handy since then, but the course is still a vivid memory for me, since that’s the clearest example I had yet… Read More
  • Cancer

    Making and Measuring Multivalency

    Here’s an unusual paper that’s studying receptor behavior on cell surfaces by use of atomic force microscopy. (Here’s the SI file, which is free to access). The authors took the marketed VEGF inhibitor vandetanib (VD6474) and attached it through linkers to the AFM tip, and then scanned around the surface of live human umbilical v… 1 48 JUNKERS JU87B-2 R-2 (PLASTIC KIT) AX07115
  • Drug Assays

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    Tamiya 1 35 Scale British Main Battle Tank Challenger Model Kit - New 351342000 A common question – well, it should be a common question, anyway – is “How do I make sure that this compound collection is a useful one to screen?” There are alternative forms that come down to the same issues – if you’re putting together a new focused screening set, what should be in it?… Read More
  • Biological News

  • Business and Markets

  • Analytical Chemistry

    A Close Look at Fragments

    Here’s a look from the D. E. Shaw research team at fragment binding, and even if you don’t do fragment-based drug discovery, it’s worth a read. That’s because the mechanisms by which fragments bind to proteins are most likely the fundamental ones by which larger molecules bind as well; this is the reductionist look at… Read More
  • Analytical Chemistry

    A Look at Proteins in Living Cells

    We spend a lot of time in this sort of work thinking about protein structures. Traditionally that’s been the province of X-ray crystallography, later joined by solution NMR, and more latterly by cryo-electron microscopy. Each of these has its own set of advantages and disadvantages, but one big split is between the solid phase (X-ray… Panda Hobby PH35005 1 35 Soviet Heavy Tank Object 279
  • Academia (vs. Industry)

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